With iOS 12.1 and later, Group FaceTime makes it easy to chat with multiple people at the same time. You can start a Group FaceTime right from the FaceTime app or from a group conversation in the Messages app. The tile of the person speaking gets larger automatically, so you’ll never lose track of the conversation. Today, Apple launched their first ad supporting Group FaceTime.
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To learn more about Group FaceTime, check Apple's support page here.